IVF is a process wherein an egg cell is fertilized with a sperm cell outside of the human body. IVF involves everything from fertilization to culturing of human gametes (egg and sperm cells) in the IVF Lab. It is an umbrella term used for a wide range of services performed in the IVF lab. IVF is also a method of fertilization where sperm is placed in the close vicinity of eggs within a petridish.
We are sure that there is no dearth of information on google that explains the procedure in details. In our attempt today, we will try to cover a brief history of the following:
In some other blog we also try and cover about how is IVF pregnancies different from natural pregnancies.
Video showing the entire IVF Process that happens in IVF Lab
IVF is not the first line of infertility treatment for patients who suffer from fertility issues.
The first step of infertility workup for a couple includes a basic fertility screening test for both partners. Such tests are usually available in any IVF Clinic. in Indore. However, many IVF Centers in Indore outsource such fertility tests to other pathology or sonography center. Try to get the fertility test done at any standard IVF Center so that the reports are standard.
Our center is one of the best IVF centers in Indore regarding fertility testing, reporting on time, and IVF results. People have rated us one of the best IVF centers in Indore due to our past performance and the overall rating on Google and other channels.
The basic fertility test for men is Semen Analysis or Semen test often colloquially called Sperm Test. Semen Analysis is done at any IVF center to assess the sperm count or sperm concentration along with sperm motility and sperm morphology. If your city does not have any good IVF center or IVF Clinic, try to get the test done from a nearby city with good IVF facility.
Baseline pelvic ultrasound, preferably transvaginal scan. An ultrasound is performed to assess ovarian reserve status as well as uterine structure of the female. The findings of the USG will reveal if there are any visible uterine anomalies/defects.
Some females will also be asked to get their tubal patency assessed using either HSG or diagnostic laparoscopy test. Tubal Patency test is performed to assess if fallopian tubes are open or closed. This test is usually not done in most IVF Clinics in Indore as it requires X-Ray machine. You may be asked to visit any Pathology lab with X-Ray facility for the test.
Once the infertility test results are out, IVF is suggested by the IVF specialist for the following causes of infertility:
Damaged or blocked fallopian tubes (can be caused by Pelvic Inflammatory Disease or prior reproductive surgery or if tubes are tied previously – tubal ligation)
Severe Endometriosis or mild to moderate Endometriosis not responding to IUI.
Advanced reproductive age, as a time to conception, is critical and pregnancy rates with other therapies are low.
Severe male factor infertility (sperm counts or sperm motility is low)-ICSI is recommended.
Severe Asthenozoospermia – very poor motility of sperms leading to male infertility.
Azoospermia – Nil Sperm report. IVF needs to be done with ICSI and TESA
Unexplained fertility problem in which other modalities have not been successful, including multiple (3 to 4) cycles of IUI.
IVF treatment is not just one simple procedure, but a series of steps interlaced with each other and done over several weeks (usually 6 weeks). The steps involved in IVF treatment that are typically followed by IVF doctor are:
Hormones (Fertility Drugs) are usually given by the IVF Specialist to stimulate the ovaries to produce more than the usual one egg per cycle. This is done to enable the collection of several eggs.The development of the eggs is monitored by blood tests and Trans Vaginal Ultrasounds that ensure eggs are collected by at precisely the right time.
These drugs used to stimulate the ovaries are one of the main contributors to IVF Cost. There are many manufacturers of IVF drugs and it is not fair to compare one manufacturer to the other. However all standard companies produce high quality IVF injections and can be administered safely.
Our IVF center in Indore specialized in highly personalized stimulation protocols for the patient, depending on their medical history, age and previous IVF cycle results.
When pregnancy is achieved using IVF Procedure, it is called IVF Pregnancy.
The only difference between care during pregnancy and normal pregnancy and IVF pregnancy would be during the first trimester,beyond which both pregnancies are treated similarly. Most of the patients and their family members unnecessarily subject themto bed rest and limited movement just because the pregnancy has resulted from IVF. It is not necessary.
IVF Cost is dependent on many factors. It is not a one price fits all.
Age of patient
Type of Infertility (Whether patient had conceived previously or not)
Reason for infertility if already known
Result of previous attempts to IVF, if patient has attempted IVF
Cost at Indore Infertility Clinic
IVF cost in Indore Infertility Clinic includes the Blastocyst Culture and Embryo Freezing cost upto one year.
Why is IVF cost different for different patients?
As explained above, the cost of IVF is majorly driven by the age of patient and ovarian reserve, hence it is best to let the IVF Specialist review your case history and reports once before he or she is ready to quote the cost of IVF cycle. You can share your reports on whatsApp with us to understand the exact cost for your case.
Also, it is important to know that not all centres charge equally, usually good IVF Center’s include the following within the IVF package cost:
IVF Cost in tier two city like Indore is lower than cities like Delhi and Mumbai usually. The cost of IVF in Indore is in therange of 1 Lakh to 1 Lakh 75 thousand when IVF is planned with self eggs and sperms.
IVF requires a significant physical, emotional, financial, and time commitment. Stress and depression are common among couples dealing with infertility. Studies have shown that reducing stress levels can drastically improve the results of IVF. Hence it is very important to keep a positive attitude during the treatment.From start to end a typical IVF treatment cycle lasts upto 6 weeks. During these six weeks, based on the Steps indicated above, a woman should expect the following:
There is no clear evidence that infertility medicines and IVF injections, if used properly, increase the risk of birth defects or cancer.
The best IVF center’s usually have very low OHSS rate as well as negligible complication rate post egg retrieval as over the years IVF stimulation protocols have become very patient friendly.
Occasionally, during Ovarian Stimulation too many follicles develop and the levels of the hormone estrogen rise too high, causing a condition called Ovarian Hyperstimulation Syndrome (OHSS). This is an unpleasant experience, which may include marked abdominal swelling, nausea, vomiting and diarrhoea, lower abdominal pain and shortness of breath. OHSS is rarely severe enough to require hospitalization.
If more than one embryo or blastocyst is transferred during an Embryo Transfer, there is always a risk of multiple birth or twin pregnancy. Multiple gestation always has a risk of premature delivery.
Even though this is a very rare case and hardly a risk at good IVF clinic’s with experienced IVF specialist who have good surgical skill, There is however a theoretical risk (very rare) of damaging other organs, or causing infection or bleeding, with the collection needle.
IVF may result in slightly increased rate of premature delivery as most of the IVF patients are usually above the age of 35 years.
The chances of ectopic pregnancy which occurs when the embryo implants at places other than the uterus,is to the order of 2 % to 7 % after an IVF Embryo Transfer. Many studies have confirmed that the rate of ectopic pregnancies after IVF is similar to the rate of ectopic pregnancy after natural conception.
The hormonal medication given prior to Embryo Transfer may cause some of the following side effects:
According to the Society of Assisted Reproductive Technologies (SART), the approximate chance of giving birth to a live baby after IVF is as follows:
41-43% for women under age 35
33-36% for women age 35 – 37
23-27% for women ages 38 – 40
13-18% for women over age 41
The main potential factors that influence pregnancy and live birth rates in IVF have been suggested to be maternal age, duration of infertility and ovarian function. Optimal woman’s age is 23–37 years at time of treatment. In women of age more than 38years, if sufficient number of their own oocytes are not available, IVF with oocyte donation is a good option. Reproductive history of female also plays an important role in IVF success, women who has given birth previously stand a better chance at succeeding with IVF attempt.
Please note that with each passing year efficiency and safety of IVF is increasing which eventually leads to improvement in take home baby rate.
IVF has a reasonable rate of success. Overall, approximately 35 percent of IVF cycles will end in a live birth after single attempt, and the cumulative chances of success are higher when more than one cycle of IVF Embryo Transfer is done.
Treatment approach. Also with newer protocols like Freeze All IVF Cycle, the chances of conception are as high as 70%.
It can be difficult to deal with the emotional highs and lows of Infertility Treatment. This is especially true if the woman (and her partner) have been trying to conceive for a long time or if there are any underlying problems in the couple’s life (eg, medical, family or partner, job, financial).
Counseling services are at times needed to counsel a couple especially after a failed IVF Cycle. Since results of IVF are best when more than one cycle is tried, it is important that a couple stays focused and positive during the entire treatment rather than being stuck upon a single failed result.
By the time a patient has been advised to undergo IVF cycle, they must have already undergone a battery of fertility tests to evaluate their reproductive health. These tests include:
After the results of the above test, the IVF specialist may put the female or both partners on dietary supplementation for few weeks to improve the quality of gametes.
Here are some tips for preparing yourself for an upcoming IVF Cycle, please read our detailed blog on the same for more information :
Find answers to common questions about IVF treatment, preparation, procedure, cost and outcomes.
IVF is a type of treatment done to help infertile patients to get pregnant and deliver healthy babies. During IVF the process of fertilization is done outside the human body within an IVF lab.
IVF cost is dependent on many factors like the patient’s age, the underlying cause of infertility, and response to ovarian stimulation. Typically IVF cost ranges from 1 lakh to 1 lakh 50 thousand in Indore. The actual cost can only be calculated after assessing the patient’s reports.
It is very important to assess the reason for IVF failure before trying another cycle. IVF can fail due to poor quality gametes (both poor sperm and poor eggs), failure to produce Blastocyst, failure of implantation, or miscarriage after implantation. Knowing the reason for failure can warrant corrective action at each step. However, in case of very advanced maternal age or very low AMH with multiple failures, your IVF specialist may advise you to think about donor oocytes or donor eggs.
During an IVF process the health of the baby born is completely dependent on the health of embryo and the course of pregnancy. Instead of being fixated on chances of abnormality, it is best to understand the following things: IVF treatment is not an elective treatment, it should be indicated and hence we should know that only couples who cannot conceive naturally will undergo IVF. So since there is no alternative to IVF our focus should be on what can be done to make it safer: Quality of eggs and sperm depend on your lifestyle and age. So maintain a healthy lifestyle and don’t be too late. Choose a good IVF center so that you know that they have a good IVF lab which consistently delivers best IVF success rate. Choose to transfer only one embryo, this will ensure an uncomplicated pregnancy. Monitor pregnancy well and stay away from stress.
IVF treatment cost is inclusive of the cost of follicular monitoring, cost of drugs for stimulating the ovaries, cost of semen processing and freezing, cost of disposables and media used in the IVF lab, and above all cost of the time that an IVF specialist doctors and embryologist gives for your case. Typically IVF treatment cost less in Indore as compared to metros however since the cost of IVF drugs and Media are costlier in non-metro cities because of transportation charges, the cost of IVF cycle in Indore is typically about 15% cheaper than in Metros. An IVF cycle can cost anywhere between 1 Lac, to 1 Lac 50 thousand if opted with self gametes.
Average number of eggs for patients under 35 years of age with regular ovarian reserve is about 8 to 10. So per IVF cycle we expect on an average 8 to 10 eggs. However for patients above 35 years of age and or poor ovarian reserve (low AMH) the average number of eggs per cycle could be as low as 5 or less.
If IVF has resulted in successful pregnancy, and progressed to the second trimester then the chances of taking home a healthy baby is very high, actually it is as high as chances in normal pregnancy.
After successful implantation of IVF embryos which is detected by bHCG blood test, the pregnancy is monitored by ultrasound to assess fetal heart beat. The chances of miscarriage in IVF pregnancy before establishment of cardiac activity is slightly higher (before 8 weeks). However the miscarriage rate after establishment of cardiac activity is similar to that of natural pregnancy.
Fertility Drugs are researched over years and show no significant rise in abnormality in the resulting baby. Nor does the ultrasound waves cause any abnormality. IUI is very safe if done under proper guidance from good IVF doctor.
Multiple pregnancies like twin pregnancy is a result of transferring more than one embryo to the uterus. Any good IVF centre will transfer only single good blastocyst which will result in a single pregnancy. However in rare incidences even a single blastocyst / embryo can result in a monozygotic twinning (identical twins).
IVF doctors will first get a few basic investigations done to assess the reason for infertility. Based on the outcome of the result, doctors will decide on the course of treatment. For male partner the investigation ordered is Semen Analysis. Female partner is advised baseline ultrasound to assess uterine cavity and or follicular monitoring.
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